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ATPγS stalls splicing after B complex formation but prior to spliceosome activation
The ATP analog ATPγS inhibits pre-mRNA splicing in vitro, but there have been conflicting reports as to which step of splicing is inhibited by this small molecule and its inhibitory mechanism remains unclear. Here we have dissected the effect of ATPγS on pre-mRNA splicing in vitro. Addition of ATPγS...
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| Pubblicato in: | RNA |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4986889/ https://ncbi.nlm.nih.gov/pubmed/27411562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.057810.116 |
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