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Structural Insights into Nuclear pre-mRNA Splicing in Higher Eukaryotes
The spliceosome is a highly complex, dynamic ribonucleoprotein molecular machine that undergoes numerous structural and compositional rearrangements that lead to the formation of its active site. Recent advances in cyroelectron microscopy (cryo-EM) have provided a plethora of near-atomic structural...
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| Pubblicato in: | Cold Spring Harb Perspect Biol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6824238/ https://ncbi.nlm.nih.gov/pubmed/30765414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a032417 |
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