Conserved Loop I of U5 Small Nuclear RNA Is Dispensable for Both Catalytic Steps of Pre-mRNA Splicing in HeLa Nuclear Extracts

The function of conserved regions of the metazoan U5 snRNA was investigated by reconstituting U5 small nuclear ribonucleoprotein particles (snRNPs) from purified snRNP proteins and HeLa or Xenopus U5 snRNA mutants and testing their ability to restore splicing to U5-depleted nuclear extracts. Substit...

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Библиографические подробности

Опубликовано в::	Mol Cell Biol
Главные авторы:	Ségault, Véronique, Will, Cindy L., Polycarpou-Schwarz, Maria, Mattaj, Iain W., Branlant, Christiane, Lührmann, Reinhard
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Taylor & Francis 1999
Предметы:	Gene Expression
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84071/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10082544/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.4.2782
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