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Conserved Loop I of U5 Small Nuclear RNA Is Dispensable for Both Catalytic Steps of Pre-mRNA Splicing in HeLa Nuclear Extracts

The function of conserved regions of the metazoan U5 snRNA was investigated by reconstituting U5 small nuclear ribonucleoprotein particles (snRNPs) from purified snRNP proteins and HeLa or Xenopus U5 snRNA mutants and testing their ability to restore splicing to U5-depleted nuclear extracts. Substit...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Ségault, Véronique, Will, Cindy L., Polycarpou-Schwarz, Maria, Mattaj, Iain W., Branlant, Christiane, Lührmann, Reinhard
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 1999
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC84071/
https://ncbi.nlm.nih.gov/pubmed/10082544
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