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A novel function for human factor C1 (HCF-1), a host protein required for herpes simplex virus infection, in pre-mRNA splicing

Human factor C1 (HCF-1) is needed for the expression of herpes simplex virus 1 (HSV-1) immediate-early genes in infected mammalian cells. Here, we provide evidence that HCF-1 is required for spliceosome assembly and splicing in mammalian nuclear extracts. HCF-1 interacts with complexes containing sp...

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Autors principals: Ajuh, Paul, Chusainow, Janet, Ryder, Ursula, Lamond, Angus I.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC136956/
https://ncbi.nlm.nih.gov/pubmed/12456665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf652
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