Identification of Small Molecule Inhibitors of Pre-mRNA Splicing

Eukaryotic pre-mRNA splicing is an essential step in gene expression for all genes that contain introns. In contrast to transcription and translation, few well characterized chemical inhibitors are available with which to dissect the splicing process, particularly in cells. Therefore, the identifica...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Pawellek, Andrea, McElroy, Stuart, Samatov, Timur, Mitchell, Lee, Woodland, Andrew, Ryder, Ursula, Gray, David, Lührmann, Reinhard, Lamond, Angus I.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
RNA
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263873/
https://ncbi.nlm.nih.gov/pubmed/25281741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.590976
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