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Epoxidation Activities of Human Cytochromes P450c17 and P450c21

[Image: see text] Some cytochrome P450 enzymes epoxidize unsaturated substrates, but this activity has not been described for the steroid hydroxylases. Physiologic steroid substrates, however, lack carbon–carbon double bonds in the parts of the pregnane molecules where steroidogenic hydroxylations o...

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Détails bibliographiques
Publié dans:Biochemistry
Auteurs principaux: Yoshimoto, Francis K., Peng, Hwei-Ming, Zhang, Haoming, Anderson, Sean M., Auchus, Richard J.
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2014
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263428/
https://ncbi.nlm.nih.gov/pubmed/25386927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi5011865
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