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Catalytic Modulation of Human Cytochromes P450 17A1 and P450 11B2 by Phospholipid

Unlike most of the drug-metabolizing cytochrome P450s, microsomal P450 17A1 and mitochondrial P450 11B2 catalyze sequential multi-step reactions in steroid biosynthesis. The membrane phospholipid composition might be one parameter that modulates the efficiency and processivity of specific pathways....

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Bibliographic Details
Published in:J Steroid Biochem Mol Biol
Main Authors: Peng, Hwei-Ming, Barlow, Chase, Auchus, Richard J.
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992074/
https://ncbi.nlm.nih.gov/pubmed/29548669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2018.03.003
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