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Catalytic Modulation of Human Cytochromes P450 17A1 and P450 11B2 by Phospholipid
Unlike most of the drug-metabolizing cytochrome P450s, microsomal P450 17A1 and mitochondrial P450 11B2 catalyze sequential multi-step reactions in steroid biosynthesis. The membrane phospholipid composition might be one parameter that modulates the efficiency and processivity of specific pathways....
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| Publicado en: | J Steroid Biochem Mol Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5992074/ https://ncbi.nlm.nih.gov/pubmed/29548669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2018.03.003 |
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