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The diverse chemistry of cytochrome P450 17A1 (P450c17, CYP17A1)
The steroid hydroxylation and carbon-carbon bond cleavage activities of cytochrome P450 17A1 (CYP17A1) are responsible for the production of glucocorticoids and androgens, respectively. The inhibition of androgen synthesis is an important strategy to treat androgen-dependent prostate cancer. We disc...
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| Publicado no: | J Steroid Biochem Mol Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4456341/ https://ncbi.nlm.nih.gov/pubmed/25482340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2014.11.026 |
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