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Why Human Cytochrome P450c21 is a Progesterone 21-Hydroxylase
Human cytochrome P450c21 (steroid 21-hydroxylase, CYP21A2)() catalyzes the 21-hydroxylation of progesterone (P4) and its preferred substrate 17α-hydroxyprogestrone (17OHP4). CYP21A2 activities, which are required for cortisol and aldosterone biosynthesis, involve the formation of energetically disfa...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3165045/ https://ncbi.nlm.nih.gov/pubmed/21446712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi102078e |
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