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The Capsid Binder Vapendavir and the Novel Protease Inhibitor SG85 Inhibit Enterovirus 71 Replication

Antivirals against enterovirus 71 (EV71) are urgently needed. We demonstrate that the novel enteroviral protease inhibitor (PI) SG85 and capsid binder (CB) vapendavir efficiently inhibit the in vitro replication of 21 EV71 strains/isolates that are representative of the different genogroups A, B, an...

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Bibliografski detalji
Izdano u:Antimicrob Agents Chemother
Glavni autori: Tijsma, Aloys, Franco, David, Tucker, Simon, Hilgenfeld, Rolf, Froeyen, Mathy, Leyssen, Pieter, Neyts, Johan
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249361/
https://ncbi.nlm.nih.gov/pubmed/25199773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03328-14
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