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The Capsid Binder Vapendavir and the Novel Protease Inhibitor SG85 Inhibit Enterovirus 71 Replication

Antivirals against enterovirus 71 (EV71) are urgently needed. We demonstrate that the novel enteroviral protease inhibitor (PI) SG85 and capsid binder (CB) vapendavir efficiently inhibit the in vitro replication of 21 EV71 strains/isolates that are representative of the different genogroups A, B, an...

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Tijsma, Aloys, Franco, David, Tucker, Simon, Hilgenfeld, Rolf, Froeyen, Mathy, Leyssen, Pieter, Neyts, Johan
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249361/
https://ncbi.nlm.nih.gov/pubmed/25199773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03328-14
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