Antiviral Activity of Broad-Spectrum and Enterovirus-Specific Inhibitors against Clinical Isolates of Enterovirus D68

We investigated the susceptibility of 10 enterovirus D68 (EV-D68) isolates (belonging to clusters A, B, and C) to (entero)virus inhibitors with different mechanisms of action. The 3C-protease inhibitors proved to be more efficient than enviroxime and pleconaril, which in turn were more effective tha...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Sun, Liang, Meijer, Adam, Froeyen, Mathy, Zhang, Linlin, Thibaut, Hendrik Jan, Baggen, Jim, George, Shyla, Vernachio, John, van Kuppeveld, Frank J. M., Leyssen, Pieter, Hilgenfeld, Rolf, Neyts, Johan, Delang, Leen
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649165/
https://ncbi.nlm.nih.gov/pubmed/26369972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01375-15
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