Understanding the Mechanism of the Broad-Spectrum Antiviral Activity of Favipiravir (T-705): Key Role of the F1 Motif of the Viral Polymerase

Favipiravir (T-705) is a broad-spectrum antiviral agent that has been approved in Japan for the treatment of influenza virus infections. T-705 also inhibits the replication of various RNA viruses, including chikungunya virus (CHIKV). We demonstrated earlier that the K291R mutation in the F1 motif of...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Abdelnabi, Rana, de Morais, Ana Theresa Silveira, Leyssen, Pieter, Imbert, Isabelle, Beaucourt, Stéphanie, Blanc, Hervé, Froeyen, Mathy, Vignuzzi, Marco, Canard, Bruno, Neyts, Johan, Delang, Leen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5446660/
https://ncbi.nlm.nih.gov/pubmed/28381577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00487-17
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados