Intra-host emergence of an enterovirus A71 variant with enhanced PSGL1 usage and neurovirulence

Enterovirus A71 (EV-A71) is one of the main causative agents of hand-foot-and-mouth disease and is occasionally associated with severe neurological complications. EV-A71 pathophysiology is poorly understood due to the lack of small animal models that robustly support viral replication in relevant or...

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Bibliographic Details
Published in:Emerg Microbes Infect
Main Authors: Sun, Liang, Tijsma, Aloys, Mirabelli, Carmen, Baggen, Jim, Wahedi, Maryam, Franco, David, De Palma, Armando, Leyssen, Pieter, Verbeken, Erik, van Kuppeveld, Frank J. M., Neyts, Johan, Thibaut, Hendrik Jan
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2019
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6711088/
https://ncbi.nlm.nih.gov/pubmed/31339457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/22221751.2019.1644142
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