Small-Molecule Inhibitors of SETD8 with Cellular Activity

[Image: see text] SETD8/SET8/Pr-SET7/KMT5A is the sole protein lysine methyltransferase (PKMT) known to monomethylate lysine 20 of histone H4 in vivo. SETD8’s methyltransferase activity has been implicated in many essential cellular processes including DNA replication, DNA damage response, transcrip...

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Detaylı Bibliyografya
Yayımlandı:ACS Chem Biol
Asıl Yazarlar: Blum, Gil, Ibáñez, Glorymar, Rao, Xiangjun, Shum, David, Radu, Constantin, Djaballah, Hakim, Rice, Judd C., Luo, Minkui
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2014
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245162/
https://ncbi.nlm.nih.gov/pubmed/25137013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500515r
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