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A Profiling Platform for the Identification of Selective Metalloprotease Inhibitors

Although proteases represent an estimated 5% to 10% of potential drug targets, inhibitors for metalloproteases (MPs) account for only a small proportion of all approved drugs, failures of which have typically been associated with lack of selectivity. In this study, the authors describe a novel and u...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: ANTCZAK, CHRISTOPHE, RADU, CONSTANTIN, DJABALLAH, HAKIM
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365505/
https://ncbi.nlm.nih.gov/pubmed/18349423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057108315877
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