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A High-Content Assay Strategy for the Identification and Profiling of ABCG2 Modulators in Live Cells

ABCG2 is a member of the ATP-binding cassette (ABC) family of transporters, the overexpression of which has been implicated in resistance to various chemotherapeutic agents. Though a number of cell-based assays to screen for inhibitors have been reported, they do not provide a content-rich platform...

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Detalhes bibliográficos
Main Authors: Antczak, Christophe, Wee, Boyoung, Radu, Constantin, Bhinder, Bhavneet, Holland, Eric C., Djaballah, Hakim
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934439/
https://ncbi.nlm.nih.gov/pubmed/23992118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2013.521
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