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A High Throughput Scintillation Proximity Imaging Assay for Protein Methyltransferases

Protein methyltransferases (PMTs) orchestrate epigenetic modifications through post-translational methylation of various protein substrates including histones. Since dysregulation of this process is widely implicated in many cancers, it is of pertinent interest to screen inhibitors of PMTs, as they...

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Hlavní autoři: Ibáñez, Glorymar, Shum, David, Blum, Gil, Bhinder, Bhavneet, Radu, Constantin, Antczak, Christophe, Luo, Minkui, Djaballah, Hakim
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553658/
https://ncbi.nlm.nih.gov/pubmed/22256970
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