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A Profiling Platform for the Identification of Selective Metalloprotease Inhibitors
Although proteases represent an estimated 5% to 10% of potential drug targets, inhibitors for metalloproteases (MPs) account for only a small proportion of all approved drugs, failures of which have typically been associated with lack of selectivity. In this study, the authors describe a novel and u...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2365505/ https://ncbi.nlm.nih.gov/pubmed/18349423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057108315877 |
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