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Small-Molecule Inhibitors of SETD8 with Cellular Activity
[Image: see text] SETD8/SET8/Pr-SET7/KMT5A is the sole protein lysine methyltransferase (PKMT) known to monomethylate lysine 20 of histone H4 in vivo. SETD8’s methyltransferase activity has been implicated in many essential cellular processes including DNA replication, DNA damage response, transcrip...
में बचाया:
| में प्रकाशित: | ACS Chem Biol |
|---|---|
| मुख्य लेखकों: | , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Chemical
Society
2014
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| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4245162/ https://ncbi.nlm.nih.gov/pubmed/25137013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500515r |
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