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Small-Molecule Inhibitors of SETD8 with Cellular Activity
[Image: see text] SETD8/SET8/Pr-SET7/KMT5A is the sole protein lysine methyltransferase (PKMT) known to monomethylate lysine 20 of histone H4 in vivo. SETD8’s methyltransferase activity has been implicated in many essential cellular processes including DNA replication, DNA damage response, transcrip...
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| Udgivet i: | ACS Chem Biol |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Chemical
Society
2014
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4245162/ https://ncbi.nlm.nih.gov/pubmed/25137013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500515r |
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