Pro-oxidant/antioxidant balance controls pancreatic β-cell differentiation through the ERK1/2 pathway

During embryogenesis, the intrauterine milieu affects cell proliferation, differentiation, and function by modifying gene expression in susceptible cells, such as the pancreatic β-cells. In this limited energy environment, mitochondrial dysfunction can lead to overproduction of reactive oxygen speci...

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Publicat a:Cell Death Dis
Autors principals: Hoarau, E, Chandra, V, Rustin, P, Scharfmann, R, Duvillie, B
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237262/
https://ncbi.nlm.nih.gov/pubmed/25341041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.441
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