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Oxygen Tension Regulates Pancreatic β-Cell Differentiation Through Hypoxia-Inducible Factor 1α
OBJECTIVE: Recent evidence indicates that low oxygen tension (pO(2)) or hypoxia controls the differentiation of several cell types during development. Variations of pO(2) are mediated through the hypoxia-inducible factor (HIF), a crucial mediator of the adaptative response of cells to hypoxia. The a...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Diabetes Association
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2828660/ https://ncbi.nlm.nih.gov/pubmed/20009089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0891 |
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