HIF1α and pancreatic β-cell development

During early embryogenesis, the pancreas shows a paucity of blood flow, and oxygen tension, the partial pressure of oxygen (pO(2)), is low. Later, the blood flow increases as β-cell differentiation occurs. We have previously reported that pO(2) controls β-cell development in rats. Here, we checked t...

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Détails bibliographiques
Auteurs principaux: Heinis, Mylène, Soggia, Andrea, Bechetoille, Camille, Simon, Marie-Thérèse, Peyssonnaux, Carole, Rustin, Pierre, Scharfmann, Raphael, Duvillié, Bertrand
Format: Artigo
Langue:Inglês
Publié: Federation of American Societies for Experimental Biology 2012
Sujets:
Research Communications
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046099/
https://ncbi.nlm.nih.gov/pubmed/22426121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-199224
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