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l-Leucine Alters Pancreatic β-Cell Differentiation and Function via the mTor Signaling Pathway

Leucine (Leu) is an essential branched-chain amino acid, which activates the mammalian target of rapamycin (mTOR) signaling pathway. The effect of Leu on cell differentiation during embryonic development is unknown. Here, we show that Leu supplementation during pregnancy significantly increased feta...

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Bibliografiske detaljer
Main Authors: Rachdi, Latif, Aïello, Virginie, Duvillié, Bertrand, Scharfmann, Raphaël
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266409/
https://ncbi.nlm.nih.gov/pubmed/22210321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0765
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