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l-Leucine Alters Pancreatic β-Cell Differentiation and Function via the mTor Signaling Pathway

Leucine (Leu) is an essential branched-chain amino acid, which activates the mammalian target of rapamycin (mTOR) signaling pathway. The effect of Leu on cell differentiation during embryonic development is unknown. Here, we show that Leu supplementation during pregnancy significantly increased feta...

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Detalhes bibliográficos
Main Authors: Rachdi, Latif, Aïello, Virginie, Duvillié, Bertrand, Scharfmann, Raphaël
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266409/
https://ncbi.nlm.nih.gov/pubmed/22210321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0765
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