l-Leucine Alters Pancreatic β-Cell Differentiation and Function via the mTor Signaling Pathway

Leucine (Leu) is an essential branched-chain amino acid, which activates the mammalian target of rapamycin (mTOR) signaling pathway. The effect of Leu on cell differentiation during embryonic development is unknown. Here, we show that Leu supplementation during pregnancy significantly increased feta...

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Main Authors: Rachdi, Latif, Aïello, Virginie, Duvillié, Bertrand, Scharfmann, Raphaël
格式: Artigo
語言:Inglês
出版: American Diabetes Association 2012
主題:
Islet Studies
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266409/
https://ncbi.nlm.nih.gov/pubmed/22210321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0765
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