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Pro-oxidant/antioxidant balance controls pancreatic β-cell differentiation through the ERK1/2 pathway
During embryogenesis, the intrauterine milieu affects cell proliferation, differentiation, and function by modifying gene expression in susceptible cells, such as the pancreatic β-cells. In this limited energy environment, mitochondrial dysfunction can lead to overproduction of reactive oxygen speci...
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| Udgivet i: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4237262/ https://ncbi.nlm.nih.gov/pubmed/25341041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.441 |
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