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Cholesterol induces pancreatic β cell apoptosis through oxidative stress pathway
Type 2 diabetes is often associated with high blood cholesterol. Here, we investigated the effect of cholesterol loading on MIN6 cells derived from pancreatic β cells. Exposure of MIN6 cells to cholesterol-induced apoptosis in time- and dose-dependent manner. Treatment with methyl-β-cyclodextrin tha...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer Netherlands
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3156264/ https://ncbi.nlm.nih.gov/pubmed/21472505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-011-0265-7 |
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