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Cholesterol induces pancreatic β cell apoptosis through oxidative stress pathway

Type 2 diabetes is often associated with high blood cholesterol. Here, we investigated the effect of cholesterol loading on MIN6 cells derived from pancreatic β cells. Exposure of MIN6 cells to cholesterol-induced apoptosis in time- and dose-dependent manner. Treatment with methyl-β-cyclodextrin tha...

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Библиографические подробности
Главные авторы: Lu, Xiuli, Liu, Jianli, Hou, Fangfang, Liu, Zhenqing, Cao, Xiangyu, Seo, Hisao, Gao, Bing
Формат: Artigo
Язык:Inglês
Опубликовано: Springer Netherlands 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156264/
https://ncbi.nlm.nih.gov/pubmed/21472505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-011-0265-7
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