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The endoplasmic reticulum stress/autophagy pathway is involved in cholesterol-induced pancreatic β-cell injury
Lipotoxicity has been implicated in pancreatic β-cell dysfunction in type 2 diabetes, but the exact mechanisms remain unknown. The current study explored the role of the endoplasmic reticulum (ER) stress pathway in cholesterol-induced lipotoxicity. Two different insulinoma cell lines were treated wi...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5353658/ https://ncbi.nlm.nih.gov/pubmed/28294183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44746 |
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