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Role of autophagy in diabetes and endoplasmic reticulum stress of pancreatic β-cells

Type 2 diabetes mellitus is characterized by insulin resistance and failure of pancreatic β-cells producing insulin. Autophagy plays a crucial role in cellular homeostasis through degradation and recycling of organelles such as mitochondria or endoplasmic reticulum (ER). Here we discussed the role o...

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Hlavní autoři: Quan, Wenying, Lim, Yu-Mi, Lee, Myung-Shik
Médium: Artigo
Jazyk:Inglês
Vydáno: Korean Society for Biochemistry and Molecular Biology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296816/
https://ncbi.nlm.nih.gov/pubmed/22257883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2012.44.2.030
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