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Cbx2 stably associates with mitotic chromosomes via a PRC2- or PRC1-independent mechanism and is needed for recruiting PRC1 complex to mitotic chromosomes

Polycomb group (PcG) proteins are epigenetic transcriptional factors that repress key developmental regulators and maintain cellular identity through mitosis via a poorly understood mechanism. Using quantitative live-cell imaging in mouse ES cells and tumor cells, we demonstrate that, although Polyc...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Zhen, Chao Yu, Duc, Huy Nguyen, Kokotovic, Marko, Phiel, Christopher J., Ren, Xiaojun
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4230780/
https://ncbi.nlm.nih.gov/pubmed/25232004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-06-1109
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