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Cbx2 stably associates with mitotic chromosomes via a PRC2- or PRC1-independent mechanism and is needed for recruiting PRC1 complex to mitotic chromosomes

Polycomb group (PcG) proteins are epigenetic transcriptional factors that repress key developmental regulators and maintain cellular identity through mitosis via a poorly understood mechanism. Using quantitative live-cell imaging in mouse ES cells and tumor cells, we demonstrate that, although Polyc...

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Publicat a:Mol Biol Cell
Autors principals: Zhen, Chao Yu, Duc, Huy Nguyen, Kokotovic, Marko, Phiel, Christopher J., Ren, Xiaojun
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4230780/
https://ncbi.nlm.nih.gov/pubmed/25232004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-06-1109
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