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Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing
In mammals X inactivation is initiated by expression of Xist RNA and involves the recruitment of Polycomb repressive complex 1 (PRC1) and 2 (PRC2), which mediate chromosome-wide ubiquitination of histone H2A and methylation of histone H3, respectively. Here, we show that PRC1 recruitment by Xist RNA...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1500994/ https://ncbi.nlm.nih.gov/pubmed/16763550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601187 |
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