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Ring1B is crucial for the regulation of developmental control genes and PRC1 proteins but not X inactivation in embryonic cells

The Polycomb group (PcG) gene Ring1B has been implicated in the repression of developmental control genes and X inactivation and is essential for embryogenesis. Ring1B protein contains a RING finger domain and functions as an E3 ubiquitin ligase that is crucial for the monoubiquitination of histone...

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Detalhes bibliográficos
Main Authors: Leeb, Martin, Wutz, Anton
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064442/
https://ncbi.nlm.nih.gov/pubmed/17620408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200612127
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