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Evolutionary diversity and developmental regulation of X-chromosome inactivation

X-chromosome inactivation (XCI) results in the transcriptional silencing of one X-chromosome in females to attain gene dosage parity between XX female and XY male mammals. Mammals appear to have developed rather diverse strategies to initiate XCI in early development. In placental mammals XCI depend...

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Detalhes bibliográficos
Main Authors: Escamilla-Del-Arenal, Martin, da Rocha, Simao Teixeira, Heard, Edith
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132430/
https://ncbi.nlm.nih.gov/pubmed/21687993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-011-1029-2
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