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Independent domains for recruitment of PRC1 and PRC2 by human XIST

XIST establishes inactivation across its chromosome of origin, even when expressed from autosomal transgenes. To identify the regions of human XIST essential for recruiting heterochromatic marks we generated a series of overlapping deletions in an autosomal inducible XIST transgene present in 8p of...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Dixon-McDougall, Thomas, Brown, Carolyn J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016261/
https://ncbi.nlm.nih.gov/pubmed/33750950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009123
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