Variant PRC1 Complex-Dependent H2A Ubiquitylation Drives PRC2 Recruitment and Polycomb Domain Formation

Chromatin modifying activities inherent to polycomb repressive complexes PRC1 and PRC2 play an essential role in gene regulation, cellular differentiation, and development. However, the mechanisms by which these complexes recognize their target sites and function together to form repressive chromati...

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Главные авторы: Blackledge, Neil P., Farcas, Anca M., Kondo, Takashi, King, Hamish W., McGouran, Joanna F., Hanssen, Lars L.P., Ito, Shinsuke, Cooper, Sarah, Kondo, Kaori, Koseki, Yoko, Ishikura, Tomoyuki, Long, Hannah K., Sheahan, Thomas W., Brockdorff, Neil, Kessler, Benedikt M., Koseki, Haruhiko, Klose, Robert J.
Формат: Artigo
Язык:Inglês
Опубликовано: Cell Press 2014
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048464/
https://ncbi.nlm.nih.gov/pubmed/24856970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.05.004
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