Variant PRC1 Complex-Dependent H2A Ubiquitylation Drives PRC2 Recruitment and Polycomb Domain Formation

Chromatin modifying activities inherent to polycomb repressive complexes PRC1 and PRC2 play an essential role in gene regulation, cellular differentiation, and development. However, the mechanisms by which these complexes recognize their target sites and function together to form repressive chromati...

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Hlavní autoři: Blackledge, Neil P., Farcas, Anca M., Kondo, Takashi, King, Hamish W., McGouran, Joanna F., Hanssen, Lars L.P., Ito, Shinsuke, Cooper, Sarah, Kondo, Kaori, Koseki, Yoko, Ishikura, Tomoyuki, Long, Hannah K., Sheahan, Thomas W., Brockdorff, Neil, Kessler, Benedikt M., Koseki, Haruhiko, Klose, Robert J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048464/
https://ncbi.nlm.nih.gov/pubmed/24856970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.05.004
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