KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands

CpG islands (CGIs) are associated with most mammalian gene promoters. A subset of CGIs act as polycomb response elements (PREs) and are recognized by the polycomb silencing systems to regulate expression of genes involved in early development. How CGIs function mechanistically as nucleation sites fo...

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Bibliographische Detailangaben
Hauptverfasser: Farcas, Anca M, Blackledge, Neil P, Sudbery, Ian, Long, Hannah K, McGouran, Joanna F, Rose, Nathan R, Lee, Sheena, Sims, David, Cerase, Andrea, Sheahan, Thomas W, Koseki, Haruhiko, Brockdorff, Neil, Ponting, Chris P, Kessler, Benedikt M, Klose, Robert J
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2012
Schlagworte:
Cell Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524939/
https://ncbi.nlm.nih.gov/pubmed/23256043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00205
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