KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands

CpG islands (CGIs) are associated with most mammalian gene promoters. A subset of CGIs act as polycomb response elements (PREs) and are recognized by the polycomb silencing systems to regulate expression of genes involved in early development. How CGIs function mechanistically as nucleation sites fo...

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Detalhes bibliográficos
Main Authors: Farcas, Anca M, Blackledge, Neil P, Sudbery, Ian, Long, Hannah K, McGouran, Joanna F, Rose, Nathan R, Lee, Sheena, Sims, David, Cerase, Andrea, Sheahan, Thomas W, Koseki, Haruhiko, Brockdorff, Neil, Ponting, Chris P, Kessler, Benedikt M, Klose, Robert J
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2012
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524939/
https://ncbi.nlm.nih.gov/pubmed/23256043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00205
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