KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands

CpG islands (CGIs) are associated with most mammalian gene promoters. A subset of CGIs act as polycomb response elements (PREs) and are recognized by the polycomb silencing systems to regulate expression of genes involved in early development. How CGIs function mechanistically as nucleation sites fo...

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Bibliografiske detaljer
Main Authors: Farcas, Anca M, Blackledge, Neil P, Sudbery, Ian, Long, Hannah K, McGouran, Joanna F, Rose, Nathan R, Lee, Sheena, Sims, David, Cerase, Andrea, Sheahan, Thomas W, Koseki, Haruhiko, Brockdorff, Neil, Ponting, Chris P, Kessler, Benedikt M, Klose, Robert J
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2012
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524939/
https://ncbi.nlm.nih.gov/pubmed/23256043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00205
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