Impact of flanking chromosomal sequences on localization and silencing by the human non-coding RNA XIST

BACKGROUND: X-chromosome inactivation is a striking example of epigenetic silencing in which expression of the long non-coding RNA XIST initiates the heterochromatinization and silencing of one of the pair of X chromosomes in mammalian females. To understand how the RNA can establish silencing acros...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Genome Biol
Hauptverfasser: Kelsey, Angela D., Yang, Christine, Leung, Danny, Minks, Jakub, Dixon-McDougall, Thomas, Baldry, Sarah E.L., Bogutz, Aaron B., Lefebvre, Louis, Brown, Carolyn J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591629/
https://ncbi.nlm.nih.gov/pubmed/26429547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0774-2
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge