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Advances in understanding chromosome silencing by the long non-coding RNA Xist
In female mammals, one of the two X chromosomes becomes genetically silenced to compensate for dosage imbalance of X-linked genes between XX females and XY males. X chromosome inactivation (X-inactivation) is a classical model for epigenetic gene regulation in mammals and has been studied for half a...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Royal Society
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3539355/ https://ncbi.nlm.nih.gov/pubmed/23166390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2011.0325 |
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