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Localized accumulation of Xist RNA in X chromosome inactivation

The non-coding RNA Xist regulates the process of X chromosome inactivation, in which one of the two X chromosomes present in cells of early female mammalian embryos is selectively and coordinately shut down. Remarkably Xist RNA functions in cis, affecting only the chromosome from which it is transcr...

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Bibliografiske detaljer
Udgivet i:Open Biol
Hovedforfatter: Brockdorff, Neil
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6936258/
https://ncbi.nlm.nih.gov/pubmed/31795917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.190213
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