A carregar...

Disruption of a conserved region of Xist exon 1 impairs Xist RNA localisation and X-linked gene silencing during random and imprinted X chromosome inactivation

In XX female mammals a single X chromosome is inactivated early in embryonic development, a process that is required to equalise X-linked gene dosage relative to XY males. X inactivation is regulated by a cis-acting master switch, the Xist locus, the product of which is a large non-coding RNA that c...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Senner, Claire E., Nesterova, Tatyana B., Norton, Sara, Dewchand, Hamlata, Godwin, Jonathan, Mak, Winifred, Brockdorff, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062423/
https://ncbi.nlm.nih.gov/pubmed/21389056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.056812
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!