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Cbx2 stably associates with mitotic chromosomes via a PRC2- or PRC1-independent mechanism and is needed for recruiting PRC1 complex to mitotic chromosomes

Polycomb group (PcG) proteins are epigenetic transcriptional factors that repress key developmental regulators and maintain cellular identity through mitosis via a poorly understood mechanism. Using quantitative live-cell imaging in mouse ES cells and tumor cells, we demonstrate that, although Polyc...

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Pubblicato in:Mol Biol Cell
Autori principali: Zhen, Chao Yu, Duc, Huy Nguyen, Kokotovic, Marko, Phiel, Christopher J., Ren, Xiaojun
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4230780/
https://ncbi.nlm.nih.gov/pubmed/25232004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-06-1109
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