Suberoylanilide Hydroxamic Acid (SAHA)-Induced Dynamics of a Human Histone Deacetylase Protein Interaction Network

Histone deacetylases (HDACs) are targets for cancer therapy. Suberoylanilide hydroxamic acid (SAHA) is an HDAC inhibitor approved by the U.S. Food and Drug Administration for the treatment of cutaneous T-cell lymphoma. To obtain a better mechanistic understanding of the Sin3/HDAC complex in cancer,...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Sardiu, Mihaela E., Smith, Karen T., Groppe, Brad D., Gilmore, Joshua M., Saraf, Anita, Egidy, Rhonda, Peak, Allison, Seidel, Chris W., Florens, Laurence, Workman, Jerry L., Washburn, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223495/
https://ncbi.nlm.nih.gov/pubmed/25073741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M113.037127
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