Suberoylanilide Hydroxamic Acid (SAHA)-Induced Dynamics of a Human Histone Deacetylase Protein Interaction Network

Histone deacetylases (HDACs) are targets for cancer therapy. Suberoylanilide hydroxamic acid (SAHA) is an HDAC inhibitor approved by the U.S. Food and Drug Administration for the treatment of cutaneous T-cell lymphoma. To obtain a better mechanistic understanding of the Sin3/HDAC complex in cancer,...

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Pubblicato in:Mol Cell Proteomics
Autori principali: Sardiu, Mihaela E., Smith, Karen T., Groppe, Brad D., Gilmore, Joshua M., Saraf, Anita, Egidy, Rhonda, Peak, Allison, Seidel, Chris W., Florens, Laurence, Workman, Jerry L., Washburn, Michael P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2014
Soggetti:
Regular Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223495/
https://ncbi.nlm.nih.gov/pubmed/25073741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M113.037127
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