Suberoylanilide Hydroxamic Acid (SAHA)-Induced Dynamics of a Human Histone Deacetylase Protein Interaction Network

Histone deacetylases (HDACs) are targets for cancer therapy. Suberoylanilide hydroxamic acid (SAHA) is an HDAC inhibitor approved by the U.S. Food and Drug Administration for the treatment of cutaneous T-cell lymphoma. To obtain a better mechanistic understanding of the Sin3/HDAC complex in cancer,...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Cell Proteomics
Main Authors: Sardiu, Mihaela E., Smith, Karen T., Groppe, Brad D., Gilmore, Joshua M., Saraf, Anita, Egidy, Rhonda, Peak, Allison, Seidel, Chris W., Florens, Laurence, Workman, Jerry L., Washburn, Michael P.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Biochemistry and Molecular Biology 2014
Teme:
Regular Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223495/
https://ncbi.nlm.nih.gov/pubmed/25073741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M113.037127
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