The Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid (SAHA) Restores Cardiomyocyte Contractility in a Rat Model of Early Diabetes

In early diabetes, hyperglycemia and the associated metabolic dysregulation promote early changes in the functional properties of cardiomyocytes, progressively leading to the appearance of the diabetic cardiomyopathy phenotype. Recently, the interplay between histone acetyltransferases (HAT) and his...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Bocchi, Leonardo, Motta, Benedetta M., Savi, Monia, Vilella, Rocchina, Meraviglia, Viviana, Rizzi, Federica, Galati, Serena, Buschini, Annamaria, Lazzaretti, Mirca, Pramstaller, Peter P., Rossini, Alessandra, Stilli, Donatella
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514644/
https://ncbi.nlm.nih.gov/pubmed/31014028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20081873
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