The Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid (SAHA) Restores Cardiomyocyte Contractility in a Rat Model of Early Diabetes

In early diabetes, hyperglycemia and the associated metabolic dysregulation promote early changes in the functional properties of cardiomyocytes, progressively leading to the appearance of the diabetic cardiomyopathy phenotype. Recently, the interplay between histone acetyltransferases (HAT) and his...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Bocchi, Leonardo, Motta, Benedetta M., Savi, Monia, Vilella, Rocchina, Meraviglia, Viviana, Rizzi, Federica, Galati, Serena, Buschini, Annamaria, Lazzaretti, Mirca, Pramstaller, Peter P., Rossini, Alessandra, Stilli, Donatella
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514644/
https://ncbi.nlm.nih.gov/pubmed/31014028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20081873
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