The histone deacetylase inhibitor Suberoylanilide Hydroxamic Acid (SAHA) as a therapeutic agent in rhabdomyosarcoma

Rhabdomyosarcoma (RMS) is an aggressive childhood sarcoma with two distinct subtypes, embryonal (ERMS) and alveolar (ARMS) histologies. More effective treatment is needed to improve outcomes, beyond conventional cytotoxic chemotherapy. The pan-histone deacetylase inhibitor, Suberoylanilide Hydroxami...

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Veröffentlicht in:Cancer Biol Ther
Hauptverfasser: Ghayad, Sandra E., Rammal, Ghina, Sarkis, Omar, Basma, Hussein, Ghamloush, Farah, Fahs, Assil, Karam, Mia, Harajli, Mohamad, Rabeh, Wissam, Mouawad, Joe E., Zalzali, Hassan, Saab, Raya
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2018
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370390/
https://ncbi.nlm.nih.gov/pubmed/30307360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2018.1529093
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