Suberoylanilide Hydroxamic Acid (SAHA)-Induced Dynamics of a Human Histone Deacetylase Protein Interaction Network

Histone deacetylases (HDACs) are targets for cancer therapy. Suberoylanilide hydroxamic acid (SAHA) is an HDAC inhibitor approved by the U.S. Food and Drug Administration for the treatment of cutaneous T-cell lymphoma. To obtain a better mechanistic understanding of the Sin3/HDAC complex in cancer,...

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Publicado en:Mol Cell Proteomics
Autores principales: Sardiu, Mihaela E., Smith, Karen T., Groppe, Brad D., Gilmore, Joshua M., Saraf, Anita, Egidy, Rhonda, Peak, Allison, Seidel, Chris W., Florens, Laurence, Workman, Jerry L., Washburn, Michael P.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2014
Materias:
Regular Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223495/
https://ncbi.nlm.nih.gov/pubmed/25073741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M113.037127
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